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Cell maintenance

How cells clean up damaged proteins and mitochondria, and what happens when they stop.

Cell maintenance 6 October 2026

Why old bodies stop clearing out “zombie cells”: a failing recycling system

A mouse study links two hallmarks of aging. When a selective protein-recycling system called chaperone-mediated autophagy declines, senescent cells change their signals and the immune cells that should eat them get worse at it.

Animal study

The Long Run is updated every night. The articles are written by an AI (Claude) from papers that anyone can read for free, and every article links to its sources. They explain research; they are not medical advice. Talk to a doctor before changing medication, diet or exercise because of a study.

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